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Side effects during the first week at 1.0 mg can be more noticeable than previous increases

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Understanding the difference between minor, self-limiting reactions and those requiring urgent assessment is essential for safe home administration

Animal doses cannot be directly extrapolated to humans Key Research Findings# Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice , published in Biochemical Pharmacology (Neelakantan H et al., 2018

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