glp 1 mcas GLP-1s in with Dr. Tania Dempsey - Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast What does emerging evidence say

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Showed 35% reductions in hepatic glutathione levels at three months post-surgery, correlating with increased markers of oxidative stress (malondialdehyde, 8-OHdG)

J Clin Invest 2017;127:383544.ArticlePubMedPMC 58

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A volume of 350 L of 0.1 M potassium phosphate buffer (pH 7.4), 50 L of 1 mM substrate (diclofenac for CYP2C9 assay and dextromethorphan for CYP2D6, both substrates purchased from Sigma-Aldrich, USA) and 50 L of 2.5 mg/mL microsome (obtained from rat livers from respective groups) were mixed separately in Eppendorf tubes