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Dysbiosis of the oral microbiota can interact with gut-associated immune cells, triggering immune responses that affect both oral and gut health

Examination of statistical heterogeneity showed low heterogeneity overall (I 2 = 34%) and no heterogeneity between diagnostic subgroups (I 2 = 0%) (Figure 4)

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As the largest metabolic organ in the human body, the gut microbiota composition and its metabolites profoundly influence distant organ function through systemic circulation