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As both H 2 O 2 and BCNU exposure led to excessive cellular GSSG accumulation, their impact on intracellular protein-GSSG adduct formation (protein S -glutathionylation) was subsequently examined in HepG2 cells by western blot analysis using a monoclonal GSSG antibody that specifically binds to GSSG-modified proteins
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What can we conclude from this study
doi: 10.1158/0008-5472.CAN-07-1872 78 SommerfeldtLPortillaHJacobsenLGjerstadJWyllerVB
Many participants lost a clinically significant share of their total body weight, which can meaningfully lower health risks over time
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