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Dore MP, Parodi G, Portoghese M, Pes GM (2021) The Controversial Role of Glucose-6-Phosphate Dehydrogenase Deficiency on Cardiovascular Disease: A Narrative Review

MAPKs are the serine/threonine protein kinases that activate the cellular stress caused by heat shock and mitogen osmotic stress, as well as inflammatory cytokines (such as TNF-, IL-1, and IL-6) [60]

N Engl J Med 373(1):1122 Ramesh N, Mortazavi S, Unniappan S (2016) Nesfatin-1 stimulates cholecystokinin and suppresses peptide YY expression and secretion in mice

The moral of the story is that tirzepatide may improve leptin sensitivity by regulating leptin and preventing resistance to this powerful satiety hormone