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When administered, NAD+ can be absorbed into tissues (or converted into precursor forms that enter cells) and may enhance the efficiency of mitochondrial energy metabolism
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Previous work has established that any residual OCR detected after oligomycin A treatment is due to non-respiratory oxygen consumption, which is usually ascribed to proton leakage through the mitochondrial inner membrane 79
doi: 10.1007/s10067-023-06612-w 47 MitchellPDSalterBMOliveriaJPEl-GammalATworekDSmithSGet al
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