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Fedwick JP, Lapointe TK, Meddings JB et al (2005) Helicobacter pylori activates myosin light-chain kinase to disrupt claudin-4 and claudin-5 and increase epithelial permeability

doi: 10.1093/nar/gkn778

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Further delving into ARA-290's potential mode of action, it is believed to engage the EPOR-cR complex, apparently initiating a cascade of signaling events