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If a day is missed, the research-sensible response is simply to resume the next scheduled dose, not to double up, because there is no acute deficit to make good and doubling only departs from the documented figure

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Neurological function: Improved neurological scores, including motor function, sensory function, and balance, as evaluated by a modified neurological severity score (mNSS)

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Gibbons C, Caudwell P, Finlayson G, Webb DL, Hellstrom PM, Naslund E et al