Additionally, skin irritation from polyphenols has been documented in some research, meaning that skincare products containing urolithin A may also have this risk.22 Finally, on the topic of pomegranate, since urolithin A is often derived from compounds of the fruit, it may interact with the same drugs (e.g., those metabolized by cytochrome P450, or CYP450, enzymes).23 24 These include but arent limited to:25 ACE inhibitors Blood pressure medications Statins (cholesterol-lowering medication) Warfarin (blood thinner) Sildenafil Anticonvulsants Sulfonylureas Buspirone (an anti-anxiety medication) Metformin Piracetam (a nootropic drug) Theophylline (used in asthma and COPD) However, Dr
Choi S, Jeong H-J, Kim H, Choi D, Cho S-C, Seong JK, et al
This is important because it suggests the anti-psoriatic activity can be localized to a specific portion of the larger protein, potentially allowing the development of small, targeted peptide therapeutics
However, the committee can only recommend actions
Virameteekul, S., Revesz, T., Jaunmuktane, Z., Warner, T
