The effect of pioglitazone on the development of cyst was also tested at the dose of 4 mg/kg bodyweight for 7 weeks, and they found that this dose was as effective as the higher dose (20 mg/kg) in lowering the cystic burden in both the male and female rats
The answer depends on your dose and how long you have been taking it
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doi: 10.3389/fcell.2023.1269724 24 de FreitasLFHamblinMR
Do Ozempic and Plaquenil (hydroxychloroquine) have interactions