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Warning signs include decreased urine output despite increased frequency attempts, dark urine, dizziness, rapid heartbeat, or confusion

In DXA body-composition analyses from the STEP 1 semaglutide program and the SURMOUNT-1 tirzepatide trial, lean mass decreased alongside fat mass, and the STEP 1 extension showed that many participants regained about two-thirds of their lost weight after stopping semaglutide, which is one more reason to protect muscle and training habits while the medication is working

Most studies report nausea rates of 40-45% at some point during treatment, though the severity is typically mild to moderate and tends to diminish over time as the body adjusts

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And I've had a lot of patients do well, but it's so little