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Safety data from trials In a paper summarizing 6 randomized, double-blind, placebo-controlled human trials, AOD 9604 did not significantly affect IGF-1 levels, did not impair glucose tolerance, and no serious adverse events (SAEs) were attributed to AOD 9604

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A schistosome-expressed immunomodulatory glycoconjugate expands peritoneal Gr1 + macrophages that suppress naive CD4 + T cell proliferation via an IFN- and nitric oxide-dependent mechanism

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