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Empagliflozin: In adult patients with type 2 diabetes mellitus with mild (eGFR: 60 to less than 90 mL/min/1.73 m2), moderate (eGFR: 30 to less than 60 mL/min/1.73 m2), and severe (eGFR: less than 30 mL/min/1.73 m2) renal impairment and patients on dialysis due to kidney failure, AUC of empagliflozin increased by approximately 18%, 20%, 66%, and 48%, respectively, compared to subjects with normal renal function

The next generation will be defined by efficacy, tolerability, safety, and oral drug properties

2) Lantus (insulin glargine) Lantus is a modified form or analog of insulin known as insulin glargine, which is longer acting than regular insulin and is indicated to improve glycemic control in adults and children with type 1 or type 2 diabetes