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Accurate purity information, typically found on the Certificate of Analysis (CoA), is crucial because it tells you the exact percentage of active compound in your powder

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Insufficient dietary intake To prevent deficiency, oral cyanocobalamin supplementation once daily 20-50 mcg or 50-150 mcg is most commonly recommended.448 In some countries, methyl- and adenosylcobalamin-containing preparations are available

Image: Dragana Gordic/Getty Images About the Authors Toni Golen, MD, Editor in Chief, Harvard Women's Health Watch

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