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Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

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Di Bonito P, Pacifico L, Licenziati MR, Maffeis C, Morandi A, Manco M, et al

Sigma-Aldrich) was used, while 0.5 M of the endoplasmic reticulum stress inducer thapsigargin (Sigma-Aldrich) was applied to activate SREBP-2, thereby upregulating genes involved in cholesterol biosynthesis and uptake [22]

Use of NSAIDs after 20 weeks of pregnancy is associated with fetal kidney problems, reduced amniotic fluid, and, in late pregnancy, premature closure of the ductus arteriosus, a cardiac structure in the fetus