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Poor phase III detox can cause estrogens and metabolites to recirculate back into the body, increasing the opportunity for DNA damage

SomanNRBaldwinSLHuGMarshJNLanzaGMHeuserJEet al

The aim is not to replace Bayesian MIPD, but to extend it toward more adaptive, trajectory-based pharmacokinetic reasoning by integrating temporally dense clinical data, evolving physiological states, and clinician-guided interpretation

Dairy food, calcium, and risk of cancer in the NIH-AARP diet and health study

The TTrials, an RCT focused on testosterone therapy in elderly men with low testosterone, included 788 men aged 65 and above (average age 72) with testosterone deficiency