If fuel partitioning is the primary mechanism, combination strategies targeting both GLP-1 and mitochondrial oxidative capacity (e.g., thyroid hormone receptor-beta agonists like resmetirom) make mechanistic sense for dual obesity-MASLD populations
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Raising Testosterone Without Losing Fat Risks and Limitations Testosterone replacement therapy (TRT) can raise testosterone to normal or even above-normal levels
FIGURE 1 Ferroptosis and Cancer A newly discovered form of cell death, different from apoptosis, autophagy, and necroptosis, called ferroptosis has recently gained recognition for use in cancer treatment