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In particular, the cystine/glutamate antiporter (System X c ), glutathione peroxidase 4 (GPX4) and glutathione (GSH) (System X c /GSH/GPX4 axis) plays a key role in preventing lipid peroxidation-mediated ferroptosis, because of which could be inhibited by blocking System X c /GSH/GPX4 axis

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You may also benefit from a B12 supplement if you have an autoimmune disease that attacks the stomach lining or GI tract (like Crohns or celiac disease), have had weight-loss surgery, or are taking heartburn medications that suppress stomach acid, Graham says

Biosci Rep (2019) 39(5):BSR20182500

Your practitioner will advise on a suitable treatment plan following consultation