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Were now seeing clinicians integrate these therapies in different ways as obesity care continues to evolve. These findings point to the need to establish evidence-based clinical protocols in this rapidly evolving area of medicine

Conversely, Hantson and coworkers [83] recently reported the case of a 47-year-old epileptic man in whom parenteral VPA therapy was associated with a severe hyperammonaemic encephalopathy (peak ammonia concentration 411 mol/l) without any biological signs of hepatotoxicity

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