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Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases

Nordmann R

The first step in the synthesis of GSH is the formation of -glutamyl-cysteine (GluCys) from the constituent amino acids glutamate and cysteine by the enzyme -glutamyl-cysteine synthetase (GCS, also called glutamate cysteine ligase (GCL))

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CCl4-treated animals showed an altered lobule structure through paraplastic connective tissue, and mild to serious fibrosis was detected (Figure 7C,E) compared to the sham group (Figure 7B,E)