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Both the stalk and ECL1 transform to a short -helix and form extensive interactions with the peptide, as shown in the previously reported peptide-bound active GCGR structure 9
Given the central position of GSH in the field of life sciences, this review aims to systematically sort out the synthesis pathway of GSH, the complex metabolic network that intersects with it, and the latest clinical applications and research progress, providing a complete knowledge framework for subsequent in-depth research on the functional mechanism of GSH and the development of treatment strategies for related diseases
Wang M, Xu R, Liu X, Zhang L, Qiu S, Lu Y, et al
10.1002/advs.202105885 75 HuangY.DaiZ.BarbacioruC.SadeW