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In a recent in vitro study using human prostate cancer cell lines DU145 and PC3, periprostatic adipose tissue promoted prostate cancer resistance to the chemotherapy drug docetaxel through a mechanism involving paracrine IGF-1 upregulation of the -tubulin isoform of tubulin Beta 2B Class IIb (TUBB2B) gene (31)

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6a) or the redox cycler, paraquat (Fig

Table 2 converts those drug-specific tiers into a bedside algorithm that tells the nurse or anaesthetist exactly how long to fast, when to scan