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A second experiment was performed with selected wash conditions of 400 mM NaCl, pH 8, and 700 mM NaCl, pH 7, in an 8-CV wash step, and similar purity was observed between the 4-CV elution samples by SDS-PAGE (Supplementary Figure S5B)

For drugs that are highly susceptible to first-pass metabolism, such as nitroglycerin, lidocaine, and propranolol, only a small fraction of the oral dose may reach the systemic circulation unchanged

CT 2.07 4.18, P = 0.024)

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