Fatty, fried, or spicy foods can exacerbate symptoms
Therefore, while the exact mechanisms controlling CHAC1 expression requires further study, a significant connection to the TP53 pathway is evident
The study indicates that the process is due to the transdifferentiation between islet cells, and the intestine-islet GLP-1/GLP-1R/PKA signal pathway is one of the important pathways to produce this process ( GLP-1 is one of the hormones responsible for the incretin effect, and exerts a wide variety of actions such as potentiation of glucose-stimulated insulin secretion, reduction of appetite, delay of gastric emptying and inhibit cell dysfunction (Yu et al., 2015
Black and Asian individuals have a higher risk of developing hyperhomocysteinemia compared with individuals of other ethnicities
We did not find a significant non-linear relationship between dose (g/day) (coefficients = 1.72, p = 0.154) and changes in FBG, but we found a significant non-linear relationship (coefficients = 7.45, p = 0.020) between duration of intervention and changes in FBG, It seems that the effective duration for decreasing of FBG is 50 weeks (Figures 4A, 5A)