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Eventually, a plateau occurs

Always check GlobalDRO.com for the current prohibited status of a substance or ingredient

Studies that used 1 mg/day in oral and intravenous trials did not show meaningfully better outcomes than lower doses, and higher doses were associated with more reports of headache, diarrhea, and gastrointestinal effects

A few commenters encouraged CMS to increase the weight of the Safety of Care domain within the existing methodology (for example, from 22 percent to 30 percent) while reducing the weight of other domains proportionally, allowing safety to have a greater influence on the Overall Hospital Quality Star Rating without introducing categorical penalties

Ethics declarations Conflict of interest The authors declare no conflict of interest