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The review also documented GSHs role in regenerating vitamin E following detoxification of lipid peroxyl radicals, its involvement in the glyoxalase systems detoxification of dicarbonyl stress induced by methylglyoxal and glyoxal, and its regulation of redox signalling through reversible S-glutathionylation of critical protein cysteine residues
Nat Cell Biol 1: 130135 Ellgaard L, Ruddock LW (2005) The human protein disulphide isomerase family: substrate interactions and functional properties
How does exercise prevent insulin resistance
The researchers also carried out a mouse study, the results of which appeared to support their findings
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