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Various studies have shown an association between being overweight or obese and the risk of developing RA

The main concerns are associated with the risks of acute hypoglycaemia as well as certain situations in which continued supply of effective insulin is not possible, for example working in very hot climates

We next assessed changes in mitochondrial morphology in intact mouse islets by confocal imaging of mitochondria from the outermost layer of islet cells, to maximise our chances of recording phenotypes from lentivirally transduced cells

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