For years, if you wanted the blood sugar and weight benefits of semaglutide the active ingredient in Ozempic and Wegovy you had to be comfortable with a weekly injection
Clinical trials of semaglutide, including the STEP (Semaglutide Treatment Effect in People with obesity) program, have shown that approximately 2540% of total weight lost may come from lean body mass, with the remainder from fat mass
Specifically, it helps individuals lose weight and maintain weight loss over the long term
Researchers are also investigating whether the effects differ based on baseline drinking severity, metabolic status, and genetic factors related to GLP-1 receptor expression and function
Time to first occurrence of expanded MACE reached nominal statistical significance and although point estimates for other outcomes were suggestive of a benefit in favour of semaglutide, wide CIs for other end points including nonfatal MI and CV death indicate substantial uncertainty