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Published 2022 Dec 8

To ensure the stability and effectiveness of blue copper peptides in skin care products, there are several key factors to consider: pH value control: GHK-Cu is unstable in a strongly acidic environment, so it needs to maintain a suitable pH value, usually a neutral or near-neutral environment, to maintain its structural integrity and biological activity

This is reflected by the activity of protective antioxidant pathways such as mitochondrial uncoupling and the Nuclear factor E2-related factor 2 (NRF2), which are weakened or bypassed in diabetes, allowing oxidative damage to accumulate [9]

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