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This is promising mechanistic evidencenot a clinical cure

Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage

Academic Press, Cambridge, pp 395413 Ullah H, de Filippis A, Khan H et al (2020a) An overview of the health benefits of Prunus species with special reference to metabolic syndrome risk factors

While neither tirzepatide nor niacinamide requires routine dose adjustment for hepatic impairment, patients with severe liver disease should be monitored closely if treatment is deemed necessary by the prescribing provider

Maintenance treatments may be advised monthly