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doi: 10.1016/S0140-6736(17)31585-4 75 ZhangLZhangLLiLHlscherC

In other cases, nationwide shortages of branded pens can lead to an involuntary pause in treatment

GLP-1 therapy should only be prescribed according to licensed indications (diabetes or obesity meeting NICE criteria), with specialist input if lymphoedema coexists

Additionally, GLP-1 receptor activation may inhibit platelet activation by increasing nitric oxide levels and decreasing P-selectin and platelet activation complex-1 expression [43]

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