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New commentary from American Association of Clinical Endocrinology (AACE) president Scott Isaacs, MD, FACP, FACE, examines the full SURPASS-CVOT dataset published in NEJM Group and shares his thoughts on what the findings mean for cardiometabolic care in patients with type 2 diabetes and established ASCVD

Rapid inactivation of these incretin hormones by DPP-4 leads to an insufficient release of insulin following oral glucose intake [31] and many of the physiological signs of T2DM, such as deteriorating glycemic control, are secondary to incretin inactivation by DPP-4

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