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During general anaesthesia, protective airway reflexes are suppressed, and if regurgitation occurs, gastric contents could enter the lungs (aspiration)

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10.1110/ps.062103006 237 HansmaH

Three things happen: gastric acid production drops dramatically, intrinsic factor production declines because most parietal cells are in the bypassed stomach, and food no longer passes through the duodenum, where the transfer to this carrier normally occurs

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