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72%), along with a reduced time needed for HE resolution and length of hospital stay, and no differences in serious adverse events

FIGURE 5 Age- and sex-dependent effects of pomegranate extract on TMAO response Although the overall effect of the pomegranate extract on plasma TMAO AUC was null ( P = 0.945), we observed that the participants with increasing TMAO were older (Figure 6A), and in particular the three oldest women ( n = 3