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Genistein, a soy isoflavone that preferentially binds to ER, has been shown to reduce hypoxia-induced hydrogen peroxide (H 2 O 2 ) production, increase Bcl-2 expression, decrease cytochrome c release from mitochondria, and significantly lower apoptosis rates associated with hypoxia (69)

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Crosstalk between melatonin and reactive oxygen species in fruits and vegetables post-harvest preservation: An update

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Dermatologists choice on 11 ingredients for hyperpigmentation What are the best ingredients you can use to treat hyperpigmentation