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C-reactive protein and inflammatory markers CRP, the most commonly measured marker of systemic inflammation, begins declining within the first three months of semaglutide treatment

Your BMI is 30 kg/m or above (or 27+ with a weight-related comorbidity including PCOS/PMOS itself) You have insulin resistance confirmed on blood tests or strongly indicated by your PCOS/PMOS picture Lifestyle changes and/or metformin havent produced sufficient results Youre not pregnant and not planning to conceive in the near term (stop Mounjaro at least 2 months before trying) You have been assessed by a clinician, including relevant blood testing Mounjaro can make a meaningful difference

Activating them promotes satiety and reduces the reward value of food

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Available online at: July 29, 2025)