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Nature 387 : 299303 Lee YI, Han YJ, Lee SY, Park SK, Park YJ, Moon HB, Shin JH, Lee JH (2003) Activation of insulin-like growth factor II signaling by mutant type p53: physiological implications for potentiation of IGF-II signaling by p53 mutant 249

In particular, histamine is a key modulator of serotonin and dopamine activity, both of which play important roles in mood regulation through the activity of reuptake enzymes DERT and SERT

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10.1016/j.immuni.2018.11.004 80 HarlowD

While it may not work as quickly as prescription medications, its safety profile and additional health benefits make it worth considering