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PMID: 41139215 Nat Commun A UFD1 variant encoding a microprotein modulates UFD1f and IPMK ubiquitination to play pivotal roles in anti-stress responses

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Treatment of White Spots Fungal infections: Antifungal creams, shampoos, oral meds Pityriasis alba: Moisturizers, gentle skin care, topical steroids Sun damage (IGH): Sunscreen, retinoid creams, laser therapy Eczema-related spots: Moisturizers, steroid creams Nutritional causes: Balanced diet & supplements under guidance Common Conditions Causing White Spots Vitiligo Fungal infections (tinea versicolor) Chronic eczema Lichen sclerosus Nutritional deficiencies When to See a Dermatologist White spots spreading quickly Painful, itchy, or changing appearance Family history of autoimmune disease or skin cancer Uncertain cause or spots not improving with care Key Takeaway White spots are not always vitiligo

UQCRC1 complexes with UQCRC2 and interacts with UQCRFS1, CYC1, and other cIII subunits to regulate cIII activity (Sunitha et al., 2016