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Some patients report that leg cramps worsen after dose increases, suggesting a dose-dependent relationship, though this remains an individual variation rather than a universal effect

The co-occurrence of high NRF2 target genes with low lipogenic genes was shared by some tissues but not all (Fig

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In addition, miR-30c targets the gene encoding microsomal triglyceride transfer protein (MTP) that is required for the lipidation of newly synthesized APOB in the liver for LD lipoprotein production