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4 Gut microbiota dysbiosis and abnormal activation of the innate immune system 4.1 Evidence for the association between complement components and schizophrenia Current studies have identified elevated transcript levels of complement components (C1qA, C3, C4, C5) in patients with schizophrenia (114) (see Table 2 ), suggesting, albeit not entirely consistently, that increased activation of the classical complement pathway may be associated with SZ

10.1080/15384101.2019.1597506 Cell Cycle 177 ZhangY.GuoS.WangS.LiX.HouD.LiH.et al (2021)

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To rescue the ipaH1.4 / ipaH2.5 -knockout strain, the wild-type or mutant ipaH1.4 gene, which has a C-terminal 6His tag gene sequence, was introduced back into the ipaH1.4 locus on the chromosome in the knockout strain by a CRISPR-Cas12a-assisted recombination method

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