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Dosing Protocol Suggested daily titration approach based on animal-to-human extrapolation

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Increase in heart rate - tell your provider if you experience a racing heartbeat while at rest

The murine mAb 18F25.1 is a non-complement-fixing subtype IgG1 and we therefore switched the subtype to complement-fixing IgG2a by engineering the 18F25.1 hybridoma cell line using CRISPR/Cas9 (Fig

1 As we age, NAD+ levels naturally decline