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To determine whether the colistin-induced depolarization was the result of the opening of the mitochondrial permeability transition pore (mPTP), mitochondria were co-incubated with colistin and cyclosporin A, a well-characterized desensitizer of the mPTP 31,32

If the goal is symptom relief through cool, drying compresses, plain cool water or pharmacy-available Domeboro solution is a safer choice with equivalent or better results

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