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Thioredoxin (Trx), present in the cytosol as Trx1 and in mitochondria as Trx2, is oxidized and upregulated in response to oxidative stress and elevated ROS levels

Glucose-dependent insulinotropic peptide secretion is induced by inflammatory stimuli in an interleukin-1-dependent manner in mice

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Participants were 49.7% male, 77.5% White, 12.6% Black or African American and 35.0% of Hispanic or Latino ethnicity