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Hyperammonaemia triggers numerous neurological and neuropsychiatric symptoms, including poor concentration, impaired memory and cognition, psychotic presentations, sleep disturbance and lethargy, and stupor and coma in severe cases

Homocysteine normalisation is a good functional marker that the B vitamin correction is working at the cellular level, not just in the serum

A 1-year controlled trial of acetyl-l-carnitine in early onset AD

monotherapy with each medication in patients with T2D and NAFLD is currently under intense investigation [121123]

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