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STEP-8 (N=338) compared semaglutide 2.4 mg weekly to liraglutide 3.0 mg daily and found semaglutide produced 15.8% mean weight loss versus 6.4% for liraglutide at 68 weeks [10]

Clinical trials reveal weight loss results of up to 20% of body weight when combined with lifestyle changes, positioning semaglutide as one of the most potent weight loss medications available

The phenomenon of deflated, hollow faces from Saxenda has not been reported- yet

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[33] broadened the scope to 26 studies ( n = 3,020), including both metabolic RCTs with secondary psychiatric outcomes and a small number of trials in clinical populations (e.g., substance use disorders)