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Coagulation disorders should be considered, particularly if heavy periods have been present since menarche or if there is a personal or family history of bleeding problems

Participants were evaluated subjectively and objectively on the first, fourth, eighth, and 12th visits

This means you absorb less than 1% of the medication you swallow, which is why oral doses are much higher than injectable doses

Hydroxocobalamin is a prescription-only medicine (POM) that should be administered by appropriately trained healthcare professionals, typically following a standard regimen of loading doses (e.g., 1mg on alternate days for 1-2 weeks) followed by maintenance doses (1mg every 2-3 months, or every 2 months if neurological symptoms are present)