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The concept of long-term stores is a simplification that overlooks the rapid metabolic turnover and the fact that a symptomatic patient may experience a swift decline in their well-being as the effects of the last injection wane

Administration approaches differ between the peptides

There are also several other underappreciated cerebellar afferent pathways (e.g., cerebellar connections with the brainstem nuclei [32]) and efferent connections (e.g., from the periaqueductal gray [33]) that we will not discuss here, but suffice it to say that cerebellar stimulation almost certainly affects many more circuits than the output pathways to the thalamus