Furthermore, several xenobiotics that have been shown to promote eryptosis, like lead, paclitaxel, cyclosporine, prostaglandin E 2 (PGE 2 ), curcumin, amphotericin B, dimethylfumerate, and chlorpromazine, can slow down the progression of malarial infection in mice or humans [230, 375, 404, 408,409,410,411]
As an analog of endogenous amylin, it is studied for its receptor-mediated signaling dynamics, sustained activation profile, and downstream neuroendocrine cascades within controlled laboratory environments
These recent experimental findings are biologically plausible, particularly as both oxidative stress and neuroinflammation are increasingly recognized as important contributors to the pathophysiology of ASD (151, 156, 160)
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2 p=0.08), and no significant publication bias as confirmed by the funnel plot (Fig