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MMWR Surveill Summ 67(3):128

The Semaglutide Oral Protocol from PlexusDx is a compounded GLP-1 agonist prescribed by licensed providers

The most sensible answer is: if you have known diabetic retinopathy, recent visual symptoms, or no recent retinal exam, then yesan updated eye evaluation is wise

If metformin is contraindicated or not tolerated, offer an SGLT-2 inhibitor and consider adding either: a GLP-1 receptor agonist for its cardiovascular, renal and glycaemic benefits or tirzepatide for its glycaemic benefits (5) Adults living with obesity If considering medicines primarily for weight management, see information about medicines for overweight and obesity in NICE's guideline on overweight and obesity management

Slows digestion, so food stays in your stomach longer