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Astrocytes take up glucose via GLUT1 and metabolize it via glycolysis, generating lactate through lactate dehydrogenase (LDH)

Naturally, there is plenty of overlap

Basal rates of gluconeogenesis ( 2 H 2 O), glucose production ([6,6- 2 H 2 ]glucose) and whole-body lipolysis ([ 2 H 5 ]glycerol) were measured after an overnight fast on study day 2

GCGR/GIPR/GLP-1R agonist: OR: 0.21, 95%CI: 0.080.56, P = 1.98 10 3 ) and the association remained consistent in the replication dataset (GIPR/GLP-1R agonist: OR: 0.16, 95%CI: 0.070.40, P = 7.90 10 5

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